Table 1 Comparison of Demographic, Clinical, Time-series Laboratory data and Imaging Characteristics between Groups
Characteristic | Infection (n = 80) | Colonization (n = 72) | Ρ value |
|---|---|---|---|
Age (y), median (IQR) | 66(53–74) | 62(51–70) | 0.173 |
Comorbidities, n (%) | |||
Hypertension | 37(46.3) | 30(41.7) | 0.570 |
Hypoproteinemia | 48(60.0) | 31(43.1) | 0.037 |
Respiratory failure | 39(37.5) | 19(26.4) | 0.143 |
Cerebrovascular disease | 12(15.0) | 3(4.2) | 0.025 |
Combined fungal, n (%) | 23(28.7) | 8(11.1) | 0.007 |
Length of hospital stay (d) | 14.29 ± 0.97 | 16.44 ± 1.36 | 0.192 |
Length of ICU stay (d) | 11.03 ± 1.11 | 9.28 ± 0.85 | 0.214 |
Duration of Oxygen supply (d) ƚ | |||
Endotracheal intubation | 6.00 ± 0.71 | 6.47 ± 0.97 | 0.691 |
Tracheotomy | 3.18 ± 0.97 | 2.57 ± 0.76 | 0.631 |
Nasal catheter | 2.08 ± 0.47 | 1.74 ± 0.63 | 0.663 |
Types of drugs, median (IQR) ƚ | |||
Glucocorticoid | 2(1–2) | 2(1–2) | 0.208 |
Antibiotics | 4(2–5) | 3(2–4) | 0.031 |
APACHEII, median (IQR) | 14(10–19) | 12(8–16) | 0.006 |
Temperature3(℃) | 37.64 ± 0.10 | 37.28 ± 0.09 | 0.009 |
Laboratory results | |||
Percentage of neutrophils§ (%) | 81.18 ± 1.07 | 81.41 ± 1.08 | 0.880 |
CRP (mg/L) § | 80.99 ± 6.17 | 77.33 ± 7.17 | 0.702 |
D-dimer (mg/mL) § | 7.03 ± 0.87 | 8.94 ± 1.53 | 0.260 |
PCT (ng/ml) § | 1.77 ± 0.46 | 1.20 ± 0.23 | 0.307 |
ΔCRP3 − 2 | 3.27 ± 7.37 | 16.56 ± 11.00 | 0.124 |
ΔWBC3 − 2 (×109/L) | 1.92 ± 1.00 | -0.55 ± 0.79 | 0.055 |
ΔD-dimer 3−2 | 0.10 ± 0.93 | -1.63 ± 1.65 | 0.348 |
ΔSerum creatinine 3−2(µmol/L) | 10.81 ± 7.84 | -13.45 ± 9.08 | 0.044 |
ΔPCT3 − 1 | -5.15 ± 2.83 | -4.37 ± 3.32 | 0.860 |
ΔD-dimer 3−1(µg/mL) | -2.48 ± 1.75 | 1.20 ± 2.40 | 0.207 |
ΔPercentage of neutrophils3 − 1 | 3.63 ± 1.83 | 7.47 ± 2.63 | 0.224 |
Pneumonia scores, median (IQR) | |||
Pneumonia scores 3§ | 15(10-21.5) | 13(9–19) | 0.108 |
ΔPneumonia scores 3−1 | 5(0–9) | 2(-3-8.5) | 0.131 |
Δpneumonia scores 3−2 | 1(-2.75-4) | -2(-5.75-1) | 0.001 |