Prognosis of mechanically ventilated patients with COVID-19 after failure of high-flow nasal cannula: a retrospective cohort study

Table 2 Parameters of ventilator from day 1 to day 3 after mechanical ventilation

	Day 1 (n = 158)		p-value	Day 2 (n = 158)		p-value	Day 3 (n = 154)		p-value
	MV (n = 51)	HFNC-F (n = 107)	p-value	MV (n = 51)	HFNC-F (n = 107)	p-value	MV (n = 47)	HFNC-F (n = 107)	p-value
MV parameter
PF ratio, mmHg	92.7 ± 8.2	151.3 ± 64.7	0.875	151.0 ± 64.0	176.2 ± 77.8	0.457	188.5 ± 83.8	169.4 ± 57.3	0.235
TV/PBW, mL/kg	6.3 ± 0.8	6.0 ± 0.7	0.446	6.3 ± 0.4	5.9 ± 0.9	0.586	6.6 ± 1.6	6.7 ± 1.4	0.533
Peak Pressure, cmH20	31.7 ± 4.3	28.5 ± 3.7	0.101	27.6 ± 3.3	25.9 ± 3.0	0.432	25.1 ± 5.2	23.8 ± 3.4	0.085
PEEP, cmH2O	14.6 ± 3.5	13.9 ± 3.2	0.881	13.3 ± 2.0	13.0 ± 1.6	0.051	10.4 ± 3.4	11.2 ± 2.4	0.118
Dynamic C, mL/cmH20	34.1 ± 13.4	31.5 ± 9.4	0.359	28.3 ± 10.8	28.4 ± 7.4	0.106	28.1 ± 10.0	31.9 ± 9.2	0.032

Data are reported as number (percentage), median [interquartile range], or mean ± standard deviation. MV: mechanical ventilation; HFNC-F: high-flow nasal cannula failure; PF ratio: arterial oxygen partial pressure/fractional inspired oxygen ratio; TV/PBW: tidal volume/predicted body weight; PEEP: positive end-expiratory pressure; C: Compliance

ISSN: 1465-993X