Elevated pulmonary vascular resistance is associated with increased lung transplant waitlist mortality among patients with chronic obstructive pulmonary disease and pulmonary hypertension: a retrospective cohort analysis

Table 3 Outcomes

	Transplant waitlist death (n = 668)	Lung transplantation (n = 5827)
Time on Waitlist (months)*	17.5 ± 8.6	7.4 ± 5.5
Pre-capillary PH (n = 3891) vs rest (n = 2604)
Pre-Capillary PH, n (%)	406 out of 3891 (10.4)	3485 out of 3891 (89.6)
Post- or combined pre- and post-capillary PH, n (%)	262 out 2604 (10.1)	2342 out of 2604 (89.9)
Severe PH (n = 543) vs non-severe PH (n = 5952)*
Severe PH, n (%)	90 out of 543 (16.6)	453 out of 543 (83.4)
Non-severe PH, n (%)	578 out of 5952 (9.7)	5374 out of 5952 (90.3)

Patients with COPD-PH who died on the lung transplant waitlist spent significantly longer time on the waitlist than those who received lung transplantation. A significantly higher proportion of patients with severe PH, as defined by PVR > 5 WU, died on the transplant waitlist as compared to those without severe PH. COPD Chronic obstructive pulmonary disease. PH Pulmonary hypertension
*p < 0.05

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