Elevated pulmonary vascular resistance is associated with increased lung transplant waitlist mortality among patients with chronic obstructive pulmonary disease and pulmonary hypertension: a retrospective cohort analysis

Table 4 Outcomes stratified by pulmonary hypertension severity

	Severe PH, n (%) (n = 543)	Non-severe PH, n (%) (n = 5952)
Mean Time on Waitlist (months)*	5.9 ± 8.6	8.6 ± 13.0
Median Time on Waitlist, months (IQR)*	2.47 (0.69–8.02)	3.52 (1.08–10.45)
Pre-capillary PH (n = 3891) vs rest (n = 2604)
Pre-Capillary PH, n (%)	472 out of 3891 (12.1)	3419 out of 3891 (87.9)
Post- or combined pre- and post-capillary PH, n (%)	71 out of 2604 (2.7)	2533 out of 2604 (97.3)
Transplant Waitlist Death (n = 668)*	90 out of 543 (16.6)	578 out of 5952 (9.7)
Lung Transplantation (n = 5827)*	453 out of 543 (83.4)	5374 out of 5952 (90.3)

Patients with COPD and severe PH (defined as PVR > 5 WU) had longer time on the waitlist along with higher mortality rate than those with COPD and non-severe PH. COPD Chronic obstructive pulmonary disease. IQR Interquartile range. PH Pulmonary hypertension. PVR Pulmonary vascular resistance
*p < 0.05

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