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Table 5 Quintile distribution of mean pulmonary artery pressure and pulmonary vascular resistance and risk of waitlist mortality

From: Elevated pulmonary vascular resistance is associated with increased lung transplant waitlist mortality among patients with chronic obstructive pulmonary disease and pulmonary hypertension: a retrospective cohort analysis

 

Number of patients

Risk of waitlist mortality

mPAP

Total n = 6495

 

 < 23 mmHg

988

Reference

 23 to < 25 mmHg

1089

HR 0.87, 95% CI 0.65–1.15, p = 0.33

 25 to < 28 mmHg

1569

HR 1.09, 95% CI 0.84–1.41, p = 0.53

 28 to < 32 mmHg

1410

HR 1.19, 95% CI 0.92–1.54, p = 0.18

 ≥ 32 mmHg

1439

HR 1.96, 95% CI 1.53–2.50, p < 0.001*

PVR

Total n = 6495

 

 < 1.86 WU

1299

Reference

 1.86 to < 2.42 WU

1291

HR 1.13, 95% CI 0.87–1.45, p = 0.36

 2.42 to < 3.01 WU

1305

HR 1.01, 95% CI 0.79–1.31, p = 0.92

 3.01 to < 3.90 WU

1301

HR 1.21, 95% CI 0.94–1.55, p = 0.14

 ≥ 3.90 WU

1299

HR 1.86, 95% CI 1.46–2.36, p < 0.001*

  1. Hazard ratios express risk of waitlist mortality in relation to the reference group. Increased risk of mortality seen in patients with mPAP ≥ 32 mmHg and in patients with PVR ≥ 3.9 WU. HR Hazard ratio. mPAP mean pulmonary artery pressure. PVR pulmonary vascular resistance. WU Woods units
  2. *Statistically significant association with increased risk of lung transplant waitlist mortality