From: Blood oxygen regulation via P2Y12R expressed in the carotid body
Normoxia | ||||||
---|---|---|---|---|---|---|
Control (littermate) | Control (6-OHDA) | Control (littermate/6-OHDA) | Control (Clopidogrel) | Control (PSB 0739) | Control (Platelet Depleted) | |
MAP (mmHg) | 97.9 ± 16.7 | 98.8 ± 17.3 | 97.1 ± 16.9 | 104.4 ± 12.8 | 100.1 ± 12.0 | 108.2 ± 10.1 |
HR (BPM) | 378.4 ± 68.6 | 375.9 ± 49.3 | 394.3 ± 65.3 | 382.1 ± 81.3 | 364.3 ± 59.3 | 416.3 ± 64.6 |
O2 Saturation (%) | 94.4 ± 1.4 | 93.2 ± 1.9 | 93.3 ± 1.3 | 93.2 ± 1.6 | 92.8 ± 1.9 | 92.9 ± 2.1 |
RR (BPM) | 144.5 ± 22.5 | 155.3 ± 23.1 | 150.9 ± 22.5 | 139.7 ± 12.9 | 134.3 ± 18.3 | 136.9 ± 8.9 |
PaO2 (mmHg) | 100.4 ± 11.6 | 102.8 ± 9.8 | 98.7 ± 6.9 | 94.2 ± 8.8 | 94.1 ± 3.1 | 91.0 ± 10.1 |
PaCO2 (mmHg) | 51.1 ± 2.9 | 45.5 ± 3.8 | 48.3 ± 6.7 | 49.7 ± 3.7 | 48.1 ± 1.4 | 46.9 ± 2.2 |
pH | 7.24 ± 0.05 | 7.24 ± 0.04 | 7.25 ± 0.03 | 7.23 ± 0.03 | 7.24 ± 0.04 | 7.28 ± 0.06 |