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Table 1 Physiological parameters of control groups preceding hypoxic challenge

From: Blood oxygen regulation via P2Y12R expressed in the carotid body

Normoxia

 

Control (littermate)

Control (6-OHDA)

Control (littermate/6-OHDA)

Control (Clopidogrel)

Control (PSB 0739)

Control (Platelet Depleted)

MAP (mmHg)

97.9 ± 16.7

98.8 ± 17.3

97.1 ± 16.9

104.4 ± 12.8

100.1 ± 12.0

108.2 ± 10.1

HR (BPM)

378.4 ± 68.6

375.9 ± 49.3

394.3 ± 65.3

382.1 ± 81.3

364.3 ± 59.3

416.3 ± 64.6

O2 Saturation (%)

94.4 ± 1.4

93.2 ± 1.9

93.3 ± 1.3

93.2 ± 1.6

92.8 ± 1.9

92.9 ± 2.1

RR (BPM)

144.5 ± 22.5

155.3 ± 23.1

150.9 ± 22.5

139.7 ± 12.9

134.3 ± 18.3

136.9 ± 8.9

PaO2 (mmHg)

100.4 ± 11.6

102.8 ± 9.8

98.7 ± 6.9

94.2 ± 8.8

94.1 ± 3.1

91.0 ± 10.1

PaCO2 (mmHg)

51.1 ± 2.9

45.5 ± 3.8

48.3 ± 6.7

49.7 ± 3.7

48.1 ± 1.4

46.9 ± 2.2

pH

7.24 ± 0.05

7.24 ± 0.04

7.25 ± 0.03

7.23 ± 0.03

7.24 ± 0.04

7.28 ± 0.06

  1. MAP mean arterial pressure, HR heart Rate, RR respiratory rate, PaO2 arterial partial O2 pressure, PaCO2 arterial partial CO2 pressure
  2. Data represent the mean ± SD. n.s., p ˃ 0.05 (one-way ANOVA with Tukey’s post-hoc test)