Characteristic | Overall cohort (n = 284) |  | Propensity-matched cohort (n = 198) | ||||
---|---|---|---|---|---|---|---|
 | 1.7 group (n = 172) | 1.1 group (n = 112) | P-value |  | 1.7 group (n = 99) | 1.1 group (n = 99) | P-value |
Age (years old, range) | 66.4 (20–91) | 65.2 (34–92) | 0.540 |  | 65.4 (20–91) | 66.1 (36–92) | 0.533 |
Male gender (%) | 97 (56.4) | 50 (44.6) | 0.053 | Â | 55 (55.6) | 46 (46.5) | 0.201 |
Scope type | Â | Â | Â | Â | Â | Â | Â |
  BF-Q290 | 83 (48.3) | 38 (33.9) | 0.012* |  | 32 (32.3) | 38 (38.4) | 0.229 |
  BF-P290 | 89 (51.7) | 74 (66.1) |  |  | 67 (67.7) | 61 (61.6) |  |
Lesion character | Â | Â | Â | Â | Â | Â | Â |
  Indication (re-biopsy, %) | 55 (32.0) | 26 (23.2) | 0.110 |  | 25 (25.3) | 26 (26.3) | 0.871 |
  Location (%) |  |  |  |  |  |  |  |
   Right upper lobe | 45 (26.2) | 38 (33.9) | 0.102 |  | 36 (36.4) | 32 (32.3) | 0.372 |
   Right middle lobe | 22 (12.8) | 11 (9.8) | 0.445 |  | 11 (11.1) | 9 (9.1) | 0.637 |
   Right lower lobe | 45 (26.2) | 23 (20.5) | 0.173 |  | 19 (19.2) | 21 (21.2) | 0.571 |
   Left upper division | 27 (15.7) | 24 (21.4) | 0.219 |  | 20 (20.2) | 22 (22.2) | 0.728 |
   Left lingual lobe | 15 (8.7) | 7 (6.3) | 0.447 |  | 6 (6.1) | 7 (7.1) | 0.774 |
   Left lower lobe | 18 (10.5) | 9 (8.0) | 0.495 |  | 7 (7.1) | 8 (8.1) | 0.788 |
   Upper lobe (right upper lobe + left upper division) | 72 (41.9) | 62 (55.4) | 0.026* |  | 56 (56.7) | 54 (54.5) | 0.775 |
  Size (mm, range) | 29.1 (8.4–71.3) | 24.8 (8-71.1) | 0.172 |  | 23.5 (8.4–59.4) | 25.9 (8.2–71.1) | 0.274 |
  Pleural distension (mm, range) | 7.3 (0-61.5) | 9.4 (0-58.3) | 0.236 |  | 10.6 (0-61.5) | 8.9 (0-58.3) | 0.304 |
  Bronchus sign (%) | 139 (80.8) | 78 (69.6) | 0.030* |  | 71 (71.7) | 72 (72.7) | 0.874 |
  Appearance (%) |  |  |  |  |  |  |  |
   Solid | 160 (93.0) | 91 (81.3) | 0.002* |  | 88 (88.9) | 88 (88.9) | 1.000 |
   Part solid | 7 (4.1) | 10 (8.9) | 0.052 |  | 7 (7.1) | 6 (6.1) | 0.774 |
   Ground glass opacity | 5 (2.9) | 11 (9.8) | 0.027* |  | 4 (4.0) | 5 (5.1) | 0.733 |
  Visibility on radiograph (%) | 143 (83.1) | 85 (75.9) | 0.134 |  | 71 (71.7) | 77 (77.8) | 0.326 |
  EBUS probe position (%) |  |  |  |  |  |  |  |
   Within | 144 (83.7) | 74 (66.1) | 0.001* |  | 72 (72.7) | 73 (73.7) | 0.872 |
   Adjacent to | 27 (15.7) | 35 (31.25) | 0.002* |  | 26 (26.3) | 25 (25.3) | 0.571 |
   Invisible | 1 (0.6) | 3 (2.7) | 0.171 |  | 1 (1.0) | 1 (1.0) | 0.751 |
  Malignant diagnosis (%) | 145 (84.3) | 84 (75) | 0.053 |  | 84 (84.8) | 82 (82.8) | 0.699 |
Procedure characteristics | Â | Â | Â | Â | Â | Â | Â |
  Intra-procedural CBCT use (%) |  |  |  |  |  |  |  |
   Total case | 33 (19.2) | 29 (25.9) | 0.117 |  | 26 (26.3) | 21 (21.2) | 0.252 |
   Solid case | 25/160 (15.6) | 14/91 (15.4) | 0.556 |  | 18/88 (20.5) | 14/88 (15.9) | 0.186 |
   Part solid case | 4/7 (57.1) | 7/10 (70) | 0.484 |  | 4/7 (57.1) | 4/6 (66.7) | 0.587 |
   Ground glass opacity case | 4/5 (80) | 8/11 (72.7) | 0.635 |  | 4/4 (100) | 3/5 (60) | 0.278 |
  Radiation dose (Gy.cm2) |  |  |  |  |  |  |  |
   Total dose | 27.3 (7.6-110.6) | 29.2 (7.5-107.2) | 0.456 |  | 30.1 (10.2-110.6) | 27.5 (7.5-105.2) | 0.463 |
   Dyna-CT dose | 24.5 (6.4–107.0) | 26.5 (6.8–103.0) | 0.459 |  | 27.5 (9.0-106.9) | 24.9 (6.8-102.2) | 0.459 |
   Fluoroscopy dose | 2.6 (0.1–11.8) | 2.6 (0.1–12.0) | 0.452 |  | 2.7 (0.1–11.8) | 2.6 (0.1–12.0) | 0.478 |
  Procedure duration (minutes, range) | 46.7 (20–196) | 49.7 (20–183) | 0.716 |  | 48.7 (20–196) | 48.5 (20–183) | 0.851 |
Complications | Â | Â | Â | Â | Â | Â | Â |
  Bleeding (%) |  |  |  |  |  |  |  |
   Severe bleeding (Grade 3 + 4) | 3 (1.7) | 2 (1.8) | 0.979 |  | 2 (2.0) | 2 (2.0) | 1.000 |
   Grade 1 | 63 (36.6) | 65 (58.0) |  |  | 25 (25.3) | 58 (58.6) |  |
   Grade 2 | 80 (46.5) | 41 (36.6) |  |  | 48 (48.5) | 38 (38.4) |  |
   Grade 3 | 2 (1.2) | 1 (0.9) |  |  | 1 (1.0) | 1 (1.0) |  |
   Grade 4 | 1 (0.6) | 1 (0.9) |  |  | 1 (1.0) | 1 (1.0) |  |
  Pneumothorax (%) | 2 (1.2) | 0 (0) | 0.252 |  | 2 (2.0) | 0 (0) | 0.155 |
  Fever (%) | 5 (2.9) | 3 (2.7) | 0.909 |  | 2 (2.0) | 3 (3.0) | 0.651 |
  Hypoxia (%) | 1 (0.6) | 1 (0.9) | 0.759 |  | 0 (0) | 1 (1.0) | 0.316 |
  Broken scope (%) | 4 (2.3) | 0 (0) | 0.104 |  | 2 (2.0) | 0 (0) | 0.155 |