Table 3 Comparison of diagnostic accuracy of 1.7-mm and 1.1-mm cryoprobes

Overall

69/99 (69.7)

80/99 (80.8)

0.050*

  Initial diagnosis

52/74 (70.3)

58/73 (79.5)

0.200

  Re-biopsy

17/25 (68)

22/26 (84.6)

0.162

P = 0.831

P = 0.566

Lesion location

  Upper lobe

37/56 (66.1)

46/54 (85.2)

0.020*

  Non-upper lobe

32/43 (74.4)

34/45 (75.6)

0.902

P = 0.370

P = 0.226

Lesion size

  > 20 mm

48/56 (85.7)

54/66 (81.8)

0.562

  ≤ 20 mm

21/43 (48.8)

26/33 (78.8)

0.008*

P < 0.001*

P = 0.718

Pleural distension

  ≥ 10 mm

34/43 (79.1)

28/32 (87.5)

0.067

  < 10 mm

35/56 (62.5)

52/67 (77.6)

0.340

P = 0.075

P = 0.243

Bronchus sign

  Presence

54/71 (76.1)

60/72 (83.3)

0.279

  Absence

15/28 (53.6)

20/27 (74.1)

0.114

P = 0.028*

P = 0.297

Lesion appearance

  Solid

64/88 (72.7)

72/88 (81.8)

0.150

  Non-solid

5/11 (45.5)

8/11 (72.7)

0.193

P = 0.064

P = 0.470

Visibility on radiograph

  Visible

51/71 (71.8)

63/77 (81.8)

0.149

  Invisible

18/28 (64.3)

17/22 (77.3)

0.320

P = 0.462

P = 0.633

EBUS probe position

  Within

52/72 (72.2)

61/73 (83.6)

0.100

  Adjacent to/invisible

17/27 (63.0)

19/26 (73.1)

0.430

P = 0.372

P = 0.244

Intra-procedural CBCT use

  Use

11/26 (42.3)

16/21 (76.2)

0.020*

  Not use

58/73 (79.5)

64/78 (82.1)

0.421

P = 0.001*

P = 0.372

Final diagnosis

  Malignancy

63/84 (75)

74/82 (90.2)

0.010*

  Benign

6/15 (40)

6/17 (35.3)

0.784

P = 0.007*

P < 0.001*