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Table 1 Description of derivation and validation cohorts

From: A simple clinical risk score (ABCDMP) for predicting mortality in patients with AECOPD and cardiovascular diseases

Characteristics

Derivation cohort

Validation cohort

With overall mortality,

n (%) or median (IQR)

Without overall

mortality, % (n) or

median (IQR)

P-Value

With overall mortality,

n (%) or median (IQR)

Without overall mortality,

n (%) or median (IQR)

P-Value

Total, n

84

2408

 

38

1208

 

Age > 75 y

67(79.8)

1415(58.8)

< 0.001

32(84.2)

666(55.1)

< 0.001

Gender

  

0.252

  

0.543

Male

59(70.2)

1823(75.7)

 

31(81.6)

935(77.4)

 

Female

25(29.8)

585(24.3)

 

7(18.4)

273(22.6)

 

Smoking (current or past)

46(54.8)

1422(59.1)

0.424

17(44.7)

691(57.2)

0.125

Diabetes

21(25.0)

450(18.7)

0.146

13(34.2)

230(19.0)

0.020

CVDs

      

 Coronary Heart Disease

33(39.3)

947(39.3)

0.994

6(15.8)

558(46.2)

< 0.001

 Heart failure

49(58.3)

1031(42.8)

0.005

25(65.8)

493(40.8)

0.002

 Heart Valve Problems

3(3.6)

188(7.8)

0.208

3(7.9)

55(4.6)

0.417

 Arrhythmia

38(45.2)

740(30.7)

0.005

16(42.1)

382(31.6)

0.172

 Stroke

22(26.2)

533(22.1)

0.380

14(36.8)

243(20.1)

0.012

Pulse > 109 beats per min

20(23.8)

257(10.7)

< 0.001

8(21.1)

129(10.7)

0.044

SBP < 90 mm Hg

3(3.6)

33(1.4)

0.119

1(2.6)

22(1.8)

0.513

DBP ≤ 60 mm Hg

24(28.6)

219(9.1)

< 0.001

11(28.9)

111(9.2)

< 0.001

Respirations ≥ 30 per min

0(0)

45(1.9)

0.403

2(5.3)

23(1.9)

0.175

Altered mental status

36(42.9)

142(5.9)

< 0.001

9(23.7)

60(5.0)

< 0.001

Anemia

58(69.0)

1240(51.7)

0.002

29(78.4)

648(53.9)

0.003

WBC > 10 × 103 mm-3

34(40.5)

632(26.3)

0.004

18(47.4)

317(26.4)

0.004

ESOR < 2%

67(81.7)

1719(72.3)

0.062

32(84.2)

830(69.6)

0.053

PH < 7.3

7(8.3)

60(2.5)

0.001

3(7.9)

35(2.9)

0.106

Serum BUN > 7 mmol/L

60(71.4)

1022(42.4)

< 0.001

32(84.2)

496(41.1)

< 0.001

NT-pro BNP > 1000 pg/ml

63(75.9)

1084(51.6)

< 0.001

27(79.4)

494(46.2)

< 0.001

Troponin T > 200 ng/L

12(15.0)

83(4.4)

< 0.001

5(13.5)

27(2.8)

< 0.001

Consolidation

87(71.3)

1242(34.2)

< 0.001

25(65.8)

445(36.8)

< 0.001

Pleural effusion

45(53.6)

697(28.9)

< 0.001

12(31.6)

388(32.1)

0.944

BAP-65

3(3–4)

2(2–3)

< 0.001

3(3–4)

2(2–3)

< 0.001

CURB-65

2(2–3)

1(1–2)

< 0.001

2(2–3)

1(1–2)

< 0.001

DECAF

3(3–4)

2(2–3)

< 0.001

3(3–4)

2(2–3)

0.003

NIVO

4(3–5)

3(2–4)

< 0.001

4(3–5)

3(2–4)

0.019

  1. Data are presented as the number of patients (%); mean ± standard deviation; median (interquartile range)
  2. Abbreviations: CVDs = cardiovascular diseases; SBP = systolic blood pressure; DBP = diastolic blood pressure; WBC = white blood cell; EOSR = eosinophil ratio; BUN = blood urea nitrogen; NT-pro BNP = N-terminal pro-B-type natriuretic peptide;
  3. Note: Anemia: hemoglobin is less than 12 g/L in females and hemoglobin is less than 13 g/L in males
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Respiratory Research

ISSN: 1465-993X

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