Table 1 Baseline characteristics of study population (n = 70)
Demographics (mean, SD) | |
Age (yr.) | 70.4 (6.95) |
Males (n%) | 68.5% |
BMI (kg/m2) | 29.4 (4.85) |
Overweight (n%) | 41.4% |
Obese (n%) | 40% |
Baseline pulmonary function tests (mean, SD) | |
FVC (in L) | 2.5 (0.76) |
FVC % predicted | 66.5 (18.13) |
DLCO (cc/sec/mmHg) | 11.2 (4.47) |
DLCO % predicted | 49.6 (16.26) |
Comorbidities (n%) | |
Coronary artery disease | 32.9% |
Hypertension | 48.5% |
Medications (n%) | |
Antifibrotics | 68.5% |
Steroids (> 10 mg/day prednisone equivalent) | 4.3% |
Functional Status (mean, SD) | |
6MWD (ft) | 991.4 (323.7) |
SGRQ | 46.3 (16.9) |
Hand-grip strength (kg) | 30.9 (10.8) |
Low hand-grip strength (n%) | 35.7% |
Frailty status | |
SHARE frailty score (mean, SD) | 1.91 (1.58) |
Frail (n%) | 34.3% |
Prefrail (n%) | 40% |
Thoracic skeletal muscle mass (mean, SD) | |
Pectoralis muscle CSA (in cm2) | 1010.8 (406.3) |
FFMI | 18.9 (1.9) |
Low FFMI (n%) | 25.7% |
Sarcopenia (n%) | 12.8% |