Table 2 Comparison of baseline characteristics of patients with low FFMI and sarcopenia and those without
FFMI | Sarcopenia | |||
|---|---|---|---|---|
Normal FFMI (n = 52) | Low FFMI (n = 18) | Nonsarcopenic (n = 61) | Sarcopenic (n = 9) | |
Age | 69.5 | 72.7 | 69.6 | 75.5 |
% Male | 69.2% | 66.7% | 68.8% | 66.7% |
BMI | 31.3*** | 23.9 | 30.4*** | 22.9 |
GAP Index | 3.9 | 4.5 | 3.9 | 5.1 |
CACI > 4 (%) | 65.4% | 83.3% | 65.5%* | 100% |
Antifibrotic therapy (%) | 69.2% | 66.7% | 70.5% | 55.5% |
Baseline FVC (L) | 2.57 | 2.35 | 2.58* | 2.06 |
Baseline FVC (%) | 66.81 | 65.72 | 67.3 | 61.2 |
Baseline DLCO (cc/sec/mmHg) | 12* | 8.8 | 11.9*** | 6.5 |
Baseline DLCO (%) | 51.73 | 43.33 | 51.7* | 35.1 |
6MWD (ft) | 1003 | 958 | 1013 | 845 |
SGRQ score | 45.91 | 47.34 | 46.17 | 47.01 |
Baseline Oxygen (%) | 36.5% | 50% | 42.6% | 22.2% |
Median Baseline O2 requirement (L/min) | 2 | 0 | 2 | 3 |
Frailty score | 1.7 | 2.4 | 1.8 | 2.8 |
% Frail | 25%* | 61.1% | 27.8%* | 77.7% |
Pectoralis muscle CSA (cm2) | 1055.7 | 881.1 | 1031 | 871 |
Hand grip strength (kg) | 31.9 | 27.7 | 32.35*** | 20.72 |
FFMI | 19.6*** | 16.8 | 19.22*** | 16.52 |
IPF exacerbations in 12 months (n) | 10 | 6 | 13 | 1 |