Table 3 Comparison of baseline characteristics of patients based on frailty and BMI category

Age

69.4

70

71.6

71.6

70.1

% Male

77.8%

67.8%

62.5%

61.5%***

70.2%

BMI

30.7

30

27.9

23.2***

30.8

GAP Index

3.3*

4

4.7*

5*

3.8

CACI > 4 (%)

55.5%

64.3%

87.2%

84.6%

66.7%

Antifibrotic use (%)

77.8%

67.8%

62.5%

61.5%

70.1%

Baseline FVC (L)

3***

2.5

2.1

1.9***

2.6

Baseline FVC (%)

76.4%*

66.1%

59.6%

57%

68.6%

Baseline DLCO (cc/sec/mmHg)

13.2**

11.7

9

7.4***

12

Baseline DLCO (%)

55.2%*

52%

42.5%

37.9**

52.2

Six-minute walk distance (ft)

1139*

981

893.2

978.2

994.5

SGRQ score

33.8***

45.3

56.8

52

44.9

Baseline Oxygen (%)

66.7%*

39.3%

20.8%

38.5%

40.3%

Median Baseline Oxygen requirement (L/min)

0

2

3

2

2

Frailty score

− 0.1***

1.8

3.6

2.6

1.7

% Frail

–

–

100%

69%**

26%

Pectoralis muscle CSA (cm²)

1098.9

1058.9

888.7

894.4

1037.4

Hand grip strength (kg)

34.3*

32.4

26.4*

25.5*

32.1

FFMI

19.5

19.1

18.2

16.5***

19.4

IPF exacerbations in 12 months (n)

5

3

8

6

10