Skip to main content

Table 2 Logistic regression analysis for risk factors of interstitial lung abnormality presence*

From: Interstitial lung abnormality evaluated by an automated quantification system: prevalence and progression rate

Characteristics

Unadjusted analysis

Multivariable analysis

OR (95% CI)

P-value

OR (95% CI)

P-value

Age, years

1.035 (1.022–1.048)

< 0.001

1.042 (1.026–1.059)

< 0.001

Male

0.763 (0.594–0.982)

0.035

0.481 (0.347–0.665)

< 0.001

Ever-smoker

0.734 (0.585–0.920)

0.007

-

-

BMI, kg/m2

1.145 (1.102–1.189)

< 0.001

1.145 (1.092–1.200)

< 0.001

WBCs, ×103/µL

1.072 (1.009–1.138)

0.024

1.071 (0.997–1.151)

0.060

Hgb, g/dL

1.006 (0.930–1.088)

0.888

-

-

Platelet, ×103/µL

1.000 (0.998–1.002)

0.857

-

-

ESR, mm/h

1.024 (1.014–1.033)

< 0.001

-

-

Glucose, mg/dL

1.004 (1.000–1.008)

0.071

-

-

HbA1c, %

1.122 (0.988–1.274)

0.077

-

-

Total cholesterol, mg/dL

1.000 (0.997–1.003)

0.818

-

-

Triglyceride, mg/dL

1.002 (1.000–1.003)

0.017

-

-

HDL, mg/dL

0.979 (0.971–0.988)

< 0.001

0.984 (0.974–0.994)

0.002

LDL, mg/dL

1.001 (0.997–1.005)

0.580

  

Protein, g/dL

1.754 (1.338–2.300)

< 0.001

1.667 (1.223–2.270)

0.001

Albumin, g/dL

0.730 (0.481–1.109)

0.140

-

-

BUN, mg/dL

1.006 (0.975–1.037)

0.726

-

-

Creatinine, mg/dL

0.803 (0.437–1.474)

0.479

-

-

FVC, predicted %

0.970 (0.960–0.980)

< 0.001

0.985 (0.973–0.997)

0.013

FEV1, predicted %

0.992 (0.983–1.001)

0.099

-

-

FEV1/FVC, %

1.015 (0.999–1.031)

0.075

1.019 (1.001–1.039)

0.043

  1. OR, odds ratio; CI, confidence interval; BMI, body mass index; WBCs, white blood cells; Hgb, haemoglobin; ESR, erythrocyte sedimentation rate; HbA1c, glycated haemoglobin; HDL, high-density lipoprotein; LDL, low-density lipoprotein; BUN, blood urea nitrogen; FVC, forced vital capacity; FEV1, forced vital capacity in 1 s; *evaluated on the basis of follow-up chest computed tomography (CT) images