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Table 3 Cox regression analysis for risk factors of interstitial lung abnormality development or progression

From: Interstitial lung abnormality evaluated by an automated quantification system: prevalence and progression rate

Characteristics

Unadjusted analysis

Multivariable analysis

HR (95% CI)

P-value

HR (95% CI)

P-value

Age, years

1.035 (1.022–1.047)

< 0.001

1.024 (1.011–1.037)

< 0.001

Male, No. (%)

0.706 (0.549–0.907)

0.007

-

-

Ever-smoker

0.806 (0.709–0.917)

0.001

0.739 (0.580–0.941)

0.014

BMI, kg/m2

1.071 (1.035–1.109)

< 0.001

1.061 (1.019–1.105)

0.004

WBCs, ×103/µL

1.028 (0.967–1.091)

0.378

-

-

Hgb, g/dL

0.997 (0.923–1.077)

0.942

-

-

Platelet, ×103/µL

1.000 (0.998–1.002)

0.918

-

-

ESR, mm/h

1.034 (1.025–1.044)

< 0.001

1.019 (1.007–1.030)

0.002

Glucose, mg/dL

1.004 (0.999–1.009)

0.132

-

-

HbA1c, %

1.086 (0.947–1.246)

0.239

-

-

Total cholesterol, mg/dL

0.999 (0.996–1.002)

0.667

-

-

Triglyceride, mg/dL

1.002 (1.000–1.003)

0.007

1.002 (1.001–1.003)

0.002

HDL, mg/dL

0.992 (0.984–1.001)

0.087

-

-

LDL, mg/dL

1.000 (0.996–1.003)

0.901

-

-

Protein, g/dL

1.486 (1.144–1.930)

0.003

1.670 (1.140–2.446)

0.008

Albumin, g/dL

0.530 (0.364–0.770)

0.001

0.455 (0.271–0.764)

0.003

BUN, mg/dL

1.015 (0.981–1.049)

0.394

-

-

Creatinine, mg/dL

0.800 (0.425–1.504)

0.488

-

-

  1. HR, hazard ratio; CI, confidence interval; BMI, body mass index; WBCs, white blood cells; Hgb, haemoglobin; ESR, erythrocyte sedimentation rate; HbA1c, glycated haemoglobin; HDL, high-density lipoprotein; LDL, low-density lipoprotein; BUN, blood urea nitrogen