Characteristics | Unadjusted analysis | Multivariable analysis | ||
---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | |
Age, years | 1.085 (1.037–1.137) | < 0.001 | 1.062 (1.012–1.115) | 0.015 |
Male | 1.976 (0.582–6.707) | 0.275 | - | - |
Ever-smokers | 3.306 (0.974–11.222) | 0.055 | 3.802 (1.044–13.842) | 0.043 |
BMI, kg/m2 | 1.003 (0.864–1.165) | 0.967 | - | - |
WBCs, ×103/µL | 1.226 (1.042–1.443) | 0.014 | - | - |
Hgb, g/dL | 0.838 (0.637–1.103) | 0.208 | - | - |
Platelet, ×103/µL | 0.999 (0.990–1.007) | 0.739 | - | - |
ESR, mm/h | 1.044 (1.022–1.066) | < 0.001 | 1.036 (1.005–1.067) | 0.021 |
Glucose, mg/dL | 1.008 (0.990–1.026) | 0.401 | - | - |
HbA1c, % | 1.476 (0.997–2.187) | 0.052 | - | - |
Total cholesterol, mg/dL | 0.987 (0.974–0.999) | 0.041 | - | - |
Triglyceride, mg/dL | 1.000 (0.995–1.006) | 0.916 | - | - |
HDL, mg/dL | 0.942 (0.902–0.984) | 0.007 | - | - |
LDL, mg/dL | 0.990 (0.977–1.004) | 0.175 | - | - |
Protein, g/dL | 0.498 (0.165–1.506) | 0.217 | - | - |
Albumin, g/dL | 0.061 (0.020–0.193) | < 0.001 | 0.173 (0.040–0.738) | 0.018 |
BUN, mg/dL | 1.070 (0.965–1.186) | 0.202 | - | - |
Creatinine, mg/dL | 2.822 (0.553–14.401) | 0.212 | - | - |
FVC, predicted % | 0.960 (0.919–1.003) | 0.069 | - | - |
FEV1, predicted % | 0.981 (0.945–1.019) | 0.324 | - | - |
FEV1/FVC, % | 0.805 (0.709–0.912) | 0.001 | - | - |