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Table 1 Overview of GWAS data used in multivariable Mendelian randomization (MVMR)

From: Association and mediation between educational attainment and respiratory diseases: a Mendelian randomization study

Phenotype

Number of participants

Number of SNP

Consortium

Author

PubMed ID

GWAS ID

Year of schooling

766,345

10,101,242

SSGAC

Lee et al.

30038396

ieu-a-1239

FEV1

321,047

19,641,887

–

Shrine N

30804560

ebi-a-GCST007432

FVC

ebi-a-GCST007429

FEV1/FVC

ebi-a-GCST007431

Lung cancer

27,209

8,945,893

ILCCO

Wang Y et al.

24880342

ieu-a-966

Asthma

408,442

34,551,291

–

Valette K et al.

34103634

ebi-a-GCST90014325

BMI

681,275

2,336,260

GIANT

Loic Yengo et al.

30124842

ieu-b-40

physical activity

215,127

15,538,177

–

Tyrrell J et al.

33563987

ebi-a-GCST90012791

Cigarettes per Day

337,334

11,913,712

GSCAN

Liu, M et al.

30643251

ieu-b-25

  1. SSGAC Social Science Genetic Association Consortium, ILCCO International Lung Cancer Consortium, GIANT Genetic Investigation of Anthropometric Traits, GSCAN GWAS & Sequencing Consortium of Alcohol and Nicotine use, EA educational attainment, BMI body mass index, FEV1 forced expiratory volume in one second, FVC forced vital capacity, FEV1/FVC forced expiratory volume in one second / forced vital capacity