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Table 5 MR directional pleiotropy test (MR Egger) of the association of educational attainment with each outcome and mediator

From: Association and mediation between educational attainment and respiratory diseases: a Mendelian randomization study

Exposure

Outcome

Egger intercept

SE

P value

EA

FVC

− 0.0006

0.0012

0.6383

FEV1

− 0.0013

0.0011

0.2441

FEV1/FVC

− 0.0004

0.0012

0.2750

Lung cancer

0.0052

0.0051

0.3098

Asthma

0.0025

0.0024

0.300

BMI

0.0004

0.0019

0.8493

Physical activity

0.0007

0.0010

0.4613

Cigarettes per day

− 0.0018

0.0022

0.4044

  1. BMI body mass index, FEV1 forced expiratory volume in one second, FVC forced vital capacity, FEV1/FVC forced expiratory volume in one second/forced vital capacity, SE standard error