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Fig. 4 | Respiratory Research

Fig. 4

From: Peroxiredoxin 3 has a crucial role in the macrophage polarization by regulating mitochondrial homeostasis

Fig. 4

Identification and validation of PRDX3 as a key protein associated with macrophage polarization. (A) PRDX3 expression was significantly decreased in lung tissue of LPS-/CLP-treated mice. (B) The PRDX3 mRNA expression was analyzed by qPCR. (C) The expression of CD68 (red) and PRDX3 (green) in lungs were examined by immunohistochemistry. (200×: bar = 50 μm, 400×: bar = 20 μm) (D) Meanwhile, PRDX3 expression was significantly decreased in macrophages. (E) The PRDX3 mRNA expression was analyzed by qPCR. *P < 0.05, **P < 0.05 vs the control group

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