Table 1 Clinical Characteristics of Study Subjects
From: Systemic IL-26 correlates with improved asthma control in children sensitized to dog allergen
Variable | Control Subjects | Allergic Subjects | P value |
|---|---|---|---|
No. of patients | 17 | 60 | |
Mean age (± SD) | 13.3 (3.0) | 13.1 (2.3) | 0.813 |
Gender (M/F) | 8/9 | 39/21 | 0.181 |
BMI (± SD) | 20.4 (3.4) | 19.8 (3.5) | 0.331 |
Allergic manifestations (%) | |||
Rhinitis | 0 (0) | 58 (97) | < 0.0001 |
Asthma | 0 (0) | 51 (85) | < 0.0001 |
Eczema, current or previous | 2 (11.8) | 38 (63) | 0.0002 |
Food Allergy | 0 (0) | 39 (65) | < 0.0001 |
ACT Score (SD) | 25.9 (1.1) | 21.4 (3.5) | < 0.0001 |
AQLQ Score (SD) | 6.96 (0.1) | 6.09 (0.8) | < 0.0001 |
Symptoms | 6.97 (0.1) | 5.91 (1.0) | < 0.0001 |
Activity Limitation | 6.97 (0.1) | 6.31 (0.9) | < 0.0001 |
Emotional Function | 7 (0) | 5.98 (1.3) | < 0.0001 |
FEV1% of predicted (SD) | 109.0 (14.8) | 100.6 (11.3) | 0.041 |
Mean IL-26 pg/mL (SEM) | ND | 73.88 (12.59) | < 0.0001 |
Mean IL-17 A pg/mL (SEM) | 18.33 (9.38) | 50.35 (6.79) | < 0.0001 |