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Table 2 Association of BMI change after COPD diagnosis for all-cause mortality and severe exacerbation

From: Longitudinal BMI change and outcomes in Chronic Obstructive Pulmonary Disease: a nationwide population-based cohort study

 

Number of incidence

(rate per 100 person-year)

Adjusteda) HR (95% CI)

All-cause mortality (N = 116,463)

Over 5% decrease

1,934 (3.5)

1.70 (1.61, 1.79)

Maintenance

4,981 (1.6)

Reference

Over 5% increase

1,497 (1.9)

1.13 (1.07, 1.20)

Severe exacerbation (N = 108,067)b)

Over 5% decrease

2,646 (6.0)

1.30 (1.24, 1.35)

Maintenance

10,804 (4.1)

Reference

Over 5% increase

3,115 (4.8)

1.12 (1.07, 1.16)

  1. a) Adjusted for age, sex, smoking status, drinking status, residential area, income, CCI, regular MVPA, previous severe exacerbation within a year before Exam 2 (baseline), medication use (ICS, LABA, or LAMA) within 1 year before Exam 2 (baseline), pulmonary TB, bronchiectasis, and pneumonia
  2. b) Patients without a history of previous severe exacerbation between COPD diagnosis and Exam 2 (baseline) were included
  3. BMI, body mass index; COPD, chronic obstructive pulmonary disease; CCI, Charlson Comorbidity Index; CI, confidence interval; HR, hazard ratio; MVPA, moderate-to-vigorous physical activity; ICS, inhaled corticosteroids; LABA, long-acting beta-2 agonist; LAMA, long-acting muscarinic agonist; TB, tuberculosis
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Respiratory Research

ISSN: 1465-993X

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