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Table 3 Association of BMI change after COPD diagnosis for all-cause mortality according to BMI before COPD diagnosis

From: Longitudinal BMI change and outcomes in Chronic Obstructive Pulmonary Disease: a nationwide population-based cohort study

 

Over 5% decrease

Adjusteda) HR (95% CI)

Maintenance

Over 5% increase

Adjusteda) HR (95% CI)

p for interaction

BMI before COPD diagnosis

   

0.05

Underweight (N = 5,545)

1.77 (1.50, 2.09)

Reference

0.87 (0.75, 1.02)

 

Normal (N = 41,286)

1.73 (1.60, 1.88)

Reference

1.03 (0.95, 1.12)

 

Overweight (N = 28,470)

1.75 (1.56, 1.97)

Reference

0.98 (0.85, 1.13)

 

Obese (N = 41,162)

1.62 (1.45, 1.80)

Reference

1.18 (1.03, 1.36)

 
  1. a) Adjusted for age, sex, smoking status, drinking status, residential area, income, CCI, regular MVPA, previous severe exacerbation within a year before Exam 2 (baseline), medication use (ICS, LABA, or LAMA) within 1 year before Exam 2 (baseline), pulmonary TB, bronchiectasis, and pneumonia
  2. BMI, body mass index; COPD, chronic obstructive pulmonary disease; CCI, Charlson Comorbidity Index; CI, confidence interval; HR, hazard ratio; MVPA, moderate-to-vigorous physical activity; ICS, inhaled corticosteroids; LABA, long-acting beta-2 agonist; LAMA, long-acting muscarinic agonist; TB, tuberculosis
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Respiratory Research

ISSN: 1465-993X

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