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Table 3 Comparison of pre-BPA and post-BPA parameters in all patients

From: Effects of right ventricular remodeling in chronic thromboembolic pulmonary hypertension on the outcomes of balloon pulmonary angioplasty: a 2D-speckle tracking echocardiography study

Variables

Before BPA

After BPA

P-value

Echocardiography

 PASP, mmHg

86.9 ± 20.5

56.5 (32.6)

 < 0.001

 TAPSE, mm

14.8 ± 3.3

17.4 ± 3.5

 < 0.001

 LVEI

1.3 (0.2)

1.1 (0.2)

 < 0.001

 TRV, cm/s

433.0 ± 58.1

350.0 (109.0)

 < 0.001

 DIVC, mm

22.4 ± 4.7

20.3 (4.9)

0.008

 S', cm/s

9.1 (2.5)

10.6 (3.3)

 < 0.001

 RIMP

0.8 (0.3)

0.6 (0.2)

 < 0.001

 FAC, %

29.4 ± 9.9

38.9 ± 10.0

 < 0.001

 RVEDA, cm2

25.3 ± 7.2

18.0 (7.8)

 < 0.001

 RVESA, cm2

18.2 ± 6.8

11.0 (6.3)

 < 0.001

 RV basal diameter, mm

45.9 ± 6.9

38.0 (9.0)

 < 0.001

 DMPA, mm

32.0 (6.2)

30.0 (5.5)

0.034

 DRPA, mm

24.0 (4.4)

23.5 (4.0)

0.180

 DLPA, mm

22.0 (4.0)

20.0 (3.3)

0.001

 LVEF, %

65.2 ± 5.1

65.3 ± 4.8

0.961

Strain parameters

 STE-RVFWLS, %

15.7 (7.6)

21.0 (10.8)

 < 0.001

 STE-RVGLS, %

13.4 ± 4.4

17.1 ± 5.1

 < 0.001

Hemodynamics

 CVP, mmHg

8.1 ± 4.1

6.0 (4.0)

0.019

 mPAP, mmHg

50.8 ± 10.4

35.5 ± 11.9

 < 0.001

 PCWP, mmHg

9.0 (5.5)

9.5 ± 3.3

0.780

 PVR, dyn·s·cm−5

888.7 ± 363.5

545.4 ± 383.8

 < 0.001

 CO, L/min

3.9 (1.4)

4.0 (1.3)

0.103

 CI, L/min/m2

2.3 ± 0.5

2.5 ± 0.6

0.014

Clinical indicators

 WHO FC

 I/II/III/IV

4/40/29/3

19/47/9/1

 < 0.001

 6WMD, m

385.5 (126.0)

454.5 (85.5)

 < 0.001

 NT-proBNP, ng/L

675.0 (1858.0)

134.0 (276.0)

 < 0.001

  1. Values are expressed as mean ± SD, median (IQR), or frequency (percentage), as appropriate
  2. Abbreviations: PASP Pulmonary artery systolic pressure by echocardiography, TAPSE Tricuspid annular plane systolic excursion, LVEI Left ventricular eccentric index, TRV Tricuspid regurgitation peak velocity, DIVC Diameter of inferior vena cava, S' Peak systolic velocity of the tricuspid annulus, RIMP Right ventricular index of myocardial performance, FAC Right ventricular fractional area change, RVEDA RV end-diastolic area, RVESA RV end-systolic area; DMPA, main pulmonary artery diameter, DRPA Right pulmonary artery diameter, DLPA Left pulmonary artery diameter, LVEF Left ventricle ejection fraction, STE-RVFWLS Speckle tracking echocardiography-RV free wall longitudinal strain, STE-RVGLS Speckle tracking echocardiography-RV global longitudinal strain, CVP Central venous pressure, mPAP Mean pulmonary artery pressure, PVR Pulmonary vascular resistance, PCWP Pulmonary capillary wedge pressure, CO Cardiac output, CI Cardiac index, WHO FC World Health Organization Functional Class, 6MWD 6 min walking distance, NT-proBNP N-terminal probrain natriuretic peptide