Fig. 9
From: TFEB regulates dendritic cell antigen presentation to modulate immune balance in asthma
Co-culture of TFEB-knockdown BMDCs with T cells remodels the balance of Th1/Th2 and Treg/Th17 cells. (A) T- bet, GATA3, Foxp3 and RORγt mRNA expression in each group. (B) The expression of IL-6, IL-12, IL-10, IFN-γ, IL-4, IL-5 and IL-13 in co-cultured cells detected by RT-qPCR. (C) Expression of IL-4, IFN-γ and IL-17 in the supernatant of co-cultured cells detected by ELISA. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001