From: TFEB regulates dendritic cell antigen presentation to modulate immune balance in asthma
 | Healthy (n = 15) | Asthma (n = 23) | p Value |
---|---|---|---|
Sex (M/F) | 10/5 | 14/9 | 0.7261 |
Age (yrs) | 7.36 (0.4140) | 6.56 (0.3021) | 0.1197 |
BMI (kg/m²) | 17.74 (1.005) | 15.68 (0.5245) | 0.0548 |
Serum total IgE level (IU/mL) | 73.52 (15.80) | 811.3 (167.1) | 0.0026 |
Allergen-specific IgE (kU/L) | 0.09556 (0.0632) | 30.11 (7.609) | 0.0124 |
Allergens, n(%) | 2 (13.33%) | 17 (73.91%) | < 0.0001 |
Dust mite | 0 (0.00%) | 12 (52.17%) | 0.0004 |
Cat | 0 (0.00%) | 2 (8.70%) | 0.2067 |
Egg white | 1 (6.67%) | 1 (4.35%) | 0.8679 |
Others | 1 (6.67%) | 2 (8.70%) | 0.7042 |
Second-hand smoke, n (%) | 6 (40.00%) | 17 (73.91%) | 0.0373 |
Familial allergy, n (%) | 2 (13.33%) | 16 (69.57%) | < 0.0001 |
Familial asthma, n (%) | 0 (0.00%) | 8 (34.78%) | 0.0031 |
FEV1 (%pred) | 102.71 (2.261) | 91.13 (1.998) | 0.0006 |
FVC (%pred) | 96.86 (2.369) | 97.87 (1.542) | 0.7118 |
FEV1/FVC Age of asthma onset, n (%) | 105.89 (1.249) | 93.14 (1.866) | < 0.0001 |