Differential expression and analysis of extrachromosomal circular DNAs as serum biomarkers in pulmonary arterial hypertension

Table 2 Correlations of eccDNA-chr2:131208878–131,424,362 with various parameters

Parameter	Correlation coefficient	P-Value
Age	0.095	0.619
BMI	0.193	0.307
6MWD	-0.399	0.029
mPAP	0.396	0.03
PCWP	0.320	0.084
PVR	0.281	0.132
CI	-0.419	0.021
NT-proBNP	0.685	P < 0.001
Troponin I	0.241	0.200
Total bilirubin	0.305	0.101
ALT	0.025	0.896
High-density lipoprotein	0.196	0.298
BUN	-0.163	0.389
Cr	0.352	0.057
UA	0.306	0.101
LVEF	-0.152	0.422
Right atrial diameters	-0.139	0.464
Right ventricular diameters	-0.091	0.633
Pulmonary artery diameter	0.290	0.127
Mitral orifice flow velocity	-0.159	0.402
Pulmonary valvular orifice velocity	-0.149	0.432

Definition of abbreviations: BMI = body mass index; 6MWD = 6-minute-walk distance; mPAP = mean pulmonary arterial pressure; PCWP = pulmonary capillary wedge pressure; PVR = pulmonary vascular resistance; CI = cardiac index; NT-proBNP = N-terminal pro–brain natriuretic peptide; BUN = blood urea nitrogen; Cr = creatinine; UA = uric acid; LVEF = left ventricular ejection fraction

ISSN: 1465-993X